Figure 3.

Brain regions showing significant associations between average accelerometer counts per minute of wear time and responses to heat pain in healthy controls.Positive correlations were found in the mid anterior and posterior cingulate cortices (image 1), a region in the lateral prefrontal cortex (image 2), the superior temporal cortex (image 3) and the posterior insular coretx (image 3). Images shown are with voxel-wise threshold set a p=0.005 and cluster size thresholding at 200 mm³. Functional timeseries data (average cluster values) for each individual were extracted and are shown plotted against physical activity values with the corresponding r-squared values.