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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: J Pain. 2011 Feb 18;12(6):640–651. doi: 10.1016/j.jpain.2010.12.004

Table 5.

Relationships between objectively monitored physical activity and brain responses to pain

Direction Peak x, y, z Cluster size (mm3) Peak r2 F-statistic
FM (n=13)
Average accelerometer counts/minute
L lateralPFC 19.5, −51.5, 22.5 456 0.80 36.0
Time spent in ADL 22.0, −52.0, 20.0 208 0.63 18.6
L lateralPFC 19.5, −51.5, 22.5 456 0.80 36.0
Time spent in moderate and vigorous activity
No significant relationships
CO (n=14)
Average accelerometer counts/minute
R lateralPFC + −29.5, −53.5, 22.5 493 0.66 22.1
Anterior MCC + −3.5, −20.5, 38.5 740 0.67 24.1
L posterior insula + 40.5, 15.5, −1.5 217 0.60 17.9
R superior temporal + −62.5, 25.5, −0.5 790 0.72 30.9
Time spent in ADL
No significant relationships
Time spent in moderate and vigorous activity
No significant relationships

All regions significant at voxel-wise threshold of p=0.005 and cluster size threshold at 200 mm3

Abbreviations: PFC, prefrontal cortex, MCC, mid-cingulate cortex, ADL, activities of daily living