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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Expert Rev Mol Diagn. 2011 Mar;11(2):159–169. doi: 10.1586/erm.10.115

Figure 3. Enrichment observed in amplicons produced by conventional PCR, full-COLD-PCR, fast-COLD-PCR and ice-COLD-PCR.

Figure 3

Data are presented for approximately 3% mutation abundance of Tm-increasing, Tm-equivalent and Tm-reducing mutations.

COLD: Coamplification at lower denaturation temperature; Tm: Melting temperature. Reproduced with permission from [28].