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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Expert Rev Mol Diagn. 2011 Mar;11(2):159–169. doi: 10.1586/erm.10.115

Figure 4. Enrichment potential for three PCR amplification strategies: conventional PCR, full-COLD-PCR and ice-COLD-PCR.

Figure 4

Enrichment is inversely related to initial mutation abundance for a melting temperature-equivalent (G>C) mutation, whereas higher enrichment potential is exhibited in lower mutation abundances. COLD: Coamplification at lower denaturation temperature.

Data taken from [28].