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Power estimates for the subgroup analysis using αs = 0.01 and 10% dropout rate given the total sample size of 1238. p is the proportion of patients in the subgroup, and σ is the common standard deviation of PTTR
| p | σ = 20% | σ = 25% | σ = 30% |
|---|---|---|---|
| 0.6 | 99.9% | 97.2% | 87.8% |
| 0.55 | 99.7% | 95.7% | 84.3% |
