Table 3.
Smoking Exposure Status |
|||||
---|---|---|---|---|---|
N=39227 | 0 | < 10 pack years | 10 to < 30 pack years | ≥ 30 pack years | P-trend* |
Events / Person-years of follow-up | 30 / 260855 | 28 / 110538 | 67 / 94648 | 49 / 33887 | - |
Age-adjusted incidence rate† | 0.12 | 0.28 | 0.72 | 1.33 | - |
Age adjusted model (n=39227) | 1.0 (Referent) | 2.30 (1.38–3.86) | 6.43 (4.18–9.89) | 11.06 (7.01–17.43) | <0.001 |
Multivariable model 1 (n=39803)‡ | 1.0 (Referent) | 2.33 (1.39–3.90) | 6.54 (4.25–10.06) | 10.76 (6.82–16.97) | <0.001 |
Multivariable model 2 (n=38960) § | 1.0 (Referent) | 2.52 (1.49–4.25) | 6.75 (4.33–10.52) | 11.09 (6.94–17.72) | <0.001 |
Data are HR (95% CI)
P for trend across categories of cigarette exposure
Incidence rates are per 1000 person-years of observation
Additionally adjusted for history of hypertension, history of diabetes, and history of hypercholesterolemia
Additionally adjusted for body mass index, alcohol consumption, and physical activity
PAD = Peripheral artery disease