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. Author manuscript; available in PMC: 2011 Jun 10.
Published in final edited form as: J Mol Neurosci. 2008 Aug 2;36(1-3):227–240. doi: 10.1007/s12031-008-9090-6

Fig. 4.

Fig. 4

The effects of intrathecal administration of PACAP-38 (30 µg i.t.) on reflex bladder activity (top trace) and EUS EMG activity (bottom trace) during continuous filling (0.21 ml/min) CMGs in a spinal cord intact decerebrate unanesthetized female rat with intact hypogastric nerves. Recordings on the left and right sides of the figure are separated by a time gap of 6 min. Each bladder contraction represents voiding. Note that PACAP-38 (injected at the arrow) produced a transient increase in peak micturition pressure and then produced a more prolonged 20–25% increase in pressure which was accompanied by a marked decrease in the EUS EMG activity. Vertical calibrations are intravesical pressure (IVP) in cm H2O and EUS EMG activity in pulses per second. EMG activity was recorded with a pulse height discriminator connected to a ratemeter. Horizontal calibration represents 5 min