Table 4.
Analysis of haplotypes frequencies and their association with PE.
| SNP | |||||||
|---|---|---|---|---|---|---|---|
| Haplotype* | rs699947 | rs1570360 | rs2010963 | rs25648 | Freq | OR (95% CI) | P value |
| 1 | C | G | C | C | 0.3851 | 1 | - |
| 2 | C | G | G | C | 0.2308 | 1.31 (0.72-2.39) | 0.38 |
| 3 | A | A | G | C | 0.1953 | 0.72 (0.37-1.37) | 0.31 |
| 4 | A | G | G | T | 0.1358 | 0.92 (0.44-1.96) | 0.84 |
| 5 | A | G | G | C | 0.015 | 1.63 (0.33-8.13) | 0.55 |
| Global haplotype association p value | 0.12 | ||||||
* The SNP order which defined the VEGF haplotype structure was rs699947, rs1570360, rs2010963, and rs25648, respectively.