Table 2.

Summary of Yeast Two-Hybrid Results

The yeast protein pairs involved in the 35 conserved interactions could be divided into several general functional groups of core biological processes as described in the Yeast Protein Database YPD (http://www.proteome.com): (1) RNA metabolism, (2) vesicular transport, (3) protein metabolism (synthesis, modification, degradation), and (4) general metabolism. The C. elegans and S. cerevisiae protein names, their corresponding BLAST E-values, and the extent of the alignment in the shortest protein for each pair is shown.