Table 2. Distribution of age, sex and histology by EBV status in Dutch cHL patients.

	all patients		EBV+		EBV-		EBV+ vs. EBV-
	n = 515		n = 181		n = 334		p-value
	n	%	n	%	n	%
sex
male	298	58	118	65	180	54	0.013*
female	217	42	63	35	154	46
histological subtype
NS	413	83	114	66	299	92	<0.001†
MC	63	13	48	28	15	4
LR	12	2	3	2	9	3
LD	9	2	7	4	2	1
NOS	18		9		9
median age (range)	37 (8–94)		43 (8–94)		34 (9–90)		<0.001‡

*Chi square test, ^† Fisher's exact test, NOS cases were excluded, ^‡ Mann Whitney U test, NS indicates nodular sclerosis; MC, mixed cellularity; LR, lymphocyte rich; LD lymphocyte depletion; NOS, not otherwise specified.