Figure 3. CnPnV infection elicits production of proinflammatory cytokines.

Cytokines detected in clarified lung tissue homogenates at day 7 in response to the sublethal inoculum (35 TCID50 units in 50 µL) including A. CCL3 (MIP-1α) B. CCL2 (MCP-1), C. CXCL10 (IP-10), D. IFNγ, and E. CXCL1 (KC); hi, heat-inactivated; n = 4 – 5 mice per time point, see also Supplemental Figure 1.