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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: J Neurochem. 2011 May 19;118(1):140–152. doi: 10.1111/j.1471-4159.2011.07289.x

Fig. 1. Effects of hypoosmotic (a) and isoosmotic low [NaCl] (b) media on the extracellular levels of L-glutamate and L-glutamine in the rat brain cortex.

Fig. 1

Brain tissue was perfused in anesthetized animals with hypoosmotic (HYPO) or isoosmotic low [NaCl] (Low-Na) media via two microdialysis probes placed bilaterally in the frontoparietal cortex. Extracellular levels of glutamate (red symbols) and glutamine (blue symbols) were measured in the microdialysate fractions using an off-line HLPC assay. The results are mean values ±SE from 5 animals. ***p<0.001, vs. basal release, repeated measures ANOVA. Note that the glutamine concentration scale is 5 times larger than the glutamate concentration scale. Data in (a) modified with permission from Haskew-Layton et al. (2008).