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. 2011 May 10;11:23. doi: 10.1186/1472-6807-11-23

Figure 9.

Figure 9

Acetyl-CoA/pyruvate omit map showing close contact and the bent conformation of Acetyl-CoA. An Fo-Fc electron density omit map contoured at 3 σ is superimposed on the the final refined model of acetyl-CoA and pyruvate in stick form. Ten rounds of refinement were performed on a model with both molecules removed, prior to map calculation. a) Stereo view of difference density showing the ~2.5 Å close contact (red dashed line). b) View of the map in the region of the active site and acetyl-CoA binding site. An intramolecular hydrogen bond also observed in the ecMSG ternary complex is shown as a green dashed line.