Table 1.
Comparison of antibody titres and prevalence measured in plasma and saliva against MSP-119 and AMA-1 P. falciparum merozoite surface antigens
| Tanzania (n = 53) | The Gambia (n = 200) | ||||
|---|---|---|---|---|---|
| Antigen | Plasma |
Saliva Oracol |
Saliva Orasure |
Plasma | Saliva |
|
AMA-1 R2 |
0.89 | 0.93 | 0.64 | ||
| Mean response (range) | 138 (1-817) |
148 (3-902) |
108* (0-871) |
317 (0-917) |
185* (45-818) |
| % positive | 47 | 34 | 36 | 36 | 30 |
|
MSP-119 r2 |
0.75 | 0.93 | 0.63 | ||
| Mean response (range) | 61 (0-769) |
62 (0-625) |
37* (0-610) |
229 (0-844) |
113* (0-612) |
| % positive | 28 | 26 | 15 | 30 | 20 |
* = significant difference between means of titre response in saliva and plasma using t-test
ND not done