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(a - h) Assessment of markers of hepatotoxicity and oxidative stress following exposure of AQ, SP and AQ+SP. Group 1: untreated control; Group 2: treated with AQ, 120 mg/kg body wt[AQ]; Group 3: treated with sulphadoxine (300 mg/kg) and pyrimethamine (15 mg/kg) [SP]; Group 4: Co-treatment of AQ and SP[AQ+SP]; [*(P < 0.05), ** (P < 0.01), *** (P < 0.001)].
