Table 1.
Baseline Characteristics and results of the SP efficacy study
Number of patients | 29 |
---|---|
Age, mean (SD), months | 34.8 (16.6) |
Sex ratio (male/female) | 1.9 (19/10) |
Weight, mean (SD), kg | 13.0 (2.5) |
Axillary temperature at admission, mean (SD), °C | 37.1 (0.95) |
Parasitaemia at admission, median (quartiles) | 18,718 (2,800-33,300) |
Day 28 PCR adjusted cure in PP analysis, n (%) Day 28 unadjusted cure in PP analysis, n (%) | 12/26 (46) 10/26 (38.5) |
Early treatment failures, n (%) | 1 (4) |
Late parasitological failures, n (%) | 13 (50) |
Parasite clearance time, mean (95%CI), hours | 61 (45-76) |
Fever clearance time, mean (95%CI), hours | 22 (14-30) |
Gametocyte carrier rate at admission, n (%) | 2 (6) |
Gametocytes carrier rate during follow-up, n (%) | 22 (85) |
SD: Standard Deviation, PCR: Polymerase Chain Reaction, CI: Confidence Interval, n: number of patients.