Table 1.
Patients characteristics and cytological, pathological, and biochemical data.
| Patients | Histology | pTNM | Duration (months) | Tg (ng/mL) | TgAb (IU/mL) | Lesions | Sites | FNA | Final diagnosis | |
|---|---|---|---|---|---|---|---|---|---|---|
| Cytology | Tg (ng/mL) | |||||||||
| 1 | PTC | pT1N1Mx | 6 | 1.0 | <60 | 1 | R II | ND | <0.2 | B |
| 2 | PTC | pT1NxMx | 15 | 4.6 | <60 | 1 | L III | Negative | 435.2 | M |
| 3 | PTC | pT1NxMx | 18 | 1.7 | <60 | 1 | R IV | CTM | 85.3 | M |
| 4 | PTC | pT1NxMx | 30 | 0.4 | <60 | 1 | R III | ND | <0.2 | B |
| 5 | PTC | pT1N0Mx | 6 | 3.1 | <60 | 1 | L II | ND | 97.2 | M |
| 6 | PTC | pT2N0Mx | 19 | 9.1 | <60 | 2 | R IV, VI | CTM | 118.5 | M |
| 7 | PTC | pT2NxMx | 47 | <0.2 | 334 | 1 | L IV | CTM | 879.4 | M |
| 8 | PTC | pT2N1Mx | 6 | 0.9 | 78 | 1 | VI | Negative | 1.1 | B |
| 9 | PTC | pT1N1Mx | 9 | 9.8 | <60 | 1 | L II | ND | 1348.6 | M |
| 10 | PTC | pT2N0Mx | 14 | 1.5 | <60 | 1 | L III | CTM | 358.5 | M |
| 11 | PTC | pT1NxMx | 8 | 12.6 | <60 | 3 | R II | CTM | 2387.4 | M |
| 12 | PTC | pT2NxMx | 16 | 9.7 | <60 | 1 | R III | CTM | 875.9 | M |
| 13 | PTC | pT1NxMx | 9 | 6.3 | <60 | 1 | R II | CTM | 958.6 | M |
| 14 | PTC | pT1N0Mx | 11 | 1.0 | <60 | 1 | L III | Negative | 48.7 | M |
| 15 | PTC | pT2N1Mx | 39 | 9.5 | <60 | 1 | L IV | CTM | >3000 | M |
| 16 | PTC | pT1NxMx | 12 | 0.8 | <60 | 1 | L III | CTM | 107.5 | M |
| 17 | PTC | pT2NxMx | 19 | 2.7 | <60 | 3 | R III-IV | ND, CTM | 541.6 | RIII B, IV M |
| 18 | PTC | pT4N1Mx | 6 | 1.6 | <60 | 1 | L III | CTM | 31.8 | M |
| 19 | PTC | pT1N1Mx | 15 | 0.5 | 289 | 1 | R IV | ND | <0.2 | B |
| 20 | PTC | pT2N1Mx | 3 | 2.3 | <60 | 1 | L III | ND | 540.7 | M |
| 21 | PTC | pT1NxMx | 34 | 4.1 | <60 | 1 | L III | CTM | 650.6 | M |
| 22 | PTC | pT2N1Mx | 8 | <0.2 | 98 | 1 | L II | ND | 5.8 | M |
| 23 | PTC | pT1NxMx | 9 | 0.8 | <60 | 2 | R II, R III | CTM | 87.5 | M |
| 24 | PTC | pT4N0Mx | 10 | 1.4 | 755 | 1 | R II | CTM | 196.4 | M |
| 25 | PTC | pT2NxMx | 21 | 11 | <60 | 1 | R III | ND | 585.3 | M |
| 26 | PTC | pT1NxMx | 9 | <0.2 | <60 | 1 | R III | Negative | <0.2 | B |
| 27 | PTC | pT4N1M | 12 | 1.1 | 160 | 1 | L III | Negative | 0.3 | B |
| 28 | PTC | pT1N0Mx | 23 | 5.3 | <60 | 1 | R III | CTM | 784.2 | M |
| 29 | PTC | pT2N1Mx | 5 | <0.2 | >1000 | 1 | R III | ND | <0.2 | B |
| 30 | PTC | pT2N0Mx | 22 | 4.9 | <60 | 1 | R III | CTM | 641.5 | M |
| 31 | PTC | pT1NxMx | 36 | 0.3 | 367 | 1 | R IV | Negative | <0.2 | B |
| 32 | PTC | pT1NxMx | 15 | 7.1 | <60 | 1 | R III | ND | 665.4 | M |
| 33 | PTC | pT2N0Mx | 41 | <0.2 | <60 | 1 | L II | Negative | <0.2 | B |
| 34 | PTC | pT1NxMx | 24 | 2.6 | <60 | 1 | R III | CTM | 570.6 | M |
| 35 | PTC | pT4N0Mx | 31 | 1.4 | >1000 | 3 | L IV, VI | CTM | 96.7 | M |
| 36 | PTC | pT4N1M | 12 | 27.1 | <60 | 1 | R II | CTM | 2987.3 | M |
| 37 | PTC | pT1N1Mx | 54 | 6.8 | <60 | 1 | L III | CTM | 875.6 | M |
| 38 | PTC | pT2NxMx | 12 | <0.2 | 149 | 1 | R IV | Negative | <0.2 | B |
| 39 | PTC | pT2N0Mx | 9 | 0.9 | <60 | 1 | R II | Negative | <0.2 | B |
| 40 | PTC | pT1N0Mx | 34 | 2.4 | 89 | 1 | L III | ND | 347.4 | M |
| 41 | PTC | pT2NxMx | 14 | 5.1 | <60 | 1 | L IV | ND | 1655.7 | M |
| 42 | PTC | pT4N1M | 8 | 7.7 | <60 | 1 | L III | Negative | 2076.5 | M |
| 43 | PTC | pT1NxMx | 61 | 1.1 | <60 | 1 | VI | Negative | <0.2 | B |
| 44 | PTC | pT2N0Mx | 22 | 1.0 | <60 | 1 | L II | CTM | 90.6 | M |
| 45 | PTC | pT2N1Mx | 12 | 6.4 | <60 | 2 | R III-IV | CTM, ND | 458.6 | RIII M, IV B |
| 46 | PTC | pT1NxMx | 45 | 0.6 | <60 | 1 | R IV | Negative | <0.2 | B |
| 47 | PTC | pT4N0Mx | 36 | 4.3 | <60 | 1 | R III | CTM | 766.4 | M |
| 48 | PTC | pT2NxMx | 11 | 1.9 | <60 | 1 | L II | ND | 306.5 | M |
| 49 | PTC | pT3NxMx | 18 | 7.0 | <60 | 1 | R III | CTM | 955.6 | M |
| 50 | PTC | pT2NxMx | 10 | 1.2 | <60 | 1 | L III | Negative | <0.2 | B |
| 51 | PTC | pT1N1Mx | 12 | 3.9 | <60 | 1 | R III | CTM | 564.7 | M |
| 52 | PTC | pT3N0Mx | 25 | 6.4 | 190 | 1 | R III | ND | 1078.6 | M |
| 53 | PTC | pT2N1Mx | 16 | 9.5 | <60 | 1 | L IV | CTM | 759.4 | M |
| 54 | PTC | pT1NxMx | 9 | 0.6 | <60 | 1 | R III | Negative | <0.2 | B |
| 55 | PTC | pT3N1Mx | 60 | <0.2 | 107 | 2 | L II-III | CTM | 137.5 | M |
| 56 | PTC | pT1N0Mx | 11 | 5.3 | <60 | 1 | R II | CTM | 654.8 | M |
| 57 | PTC | pT2N1Mx | 18 | 1.1 | 860 | 1 | L III | ND | <0.2 | B |
| 58 | PTC | pT1NxMx | 9 | 0.9 | <60 | 1 | R IV | Negative | <0.2 | B |
| 59 | PTC | pT2NxMx | 28 | 1.1 | <60 | 1 | R III | ND | 99.6 | M |
| 60 | PTC-TCV | pT3NxMx | 13 | 4.6 | <60 | 1 | L II | CTM | 436.8 | M |
| 61 | PTC | pT1NxMx | 2 | 2.7 | <60 | 1 | R II | CTM | 194.5 | M |
| 62 | PTC | pT3NxMx | 7 | 21.9 | <60 | 3 | R III, L II | Neg., CTM | >3000 | RIII B, LII M |
| 63 | PTC | pT1NxMx | 18 | 1.1 | <60 | 1 | R III | CTM | 27.4 | M |
| 64 | PTC | pT3NxMx | 10 | 3.5 | <60 | 1 | VI | CTM | 147.4 | M |
| 65 | PTC | pT2N0Mx | 29 | <0.2 | >1000 | 1 | R IV | Negative | <0.2 | B |
| 66 | PTC | pT3N1Mx | 6 | 5.6 | <60 | 1 | L III | CTM | <0.2 | M |
| 67 | PTC | pT1N1Mx | 11 | 2.1 | <60 | 1 | R III | ND | <0.2 | M |
| 68 | PTC | pT3N0Mx | 18 | 0.7 | <60 | 1 | R III | ND | <0.2 | B |
| 69 | PTC | pT2N0Mx | 23 | 1.7 | <60 | 1 | L IV | CTM | 75.6 | M |
| 70 | PTC | pT1NxMx | 9 | 3.5 | <60 | 1 | L II | ND | 72.6 | M |
| 71 | PTC | pT3N0Mx | 18 | 7.1 | <60 | 2 | R IV, VI | CTM | 386.2 | RIV B, VI M |
| 72 | PTC | pT1NxMx | 7 | 1.8 | 1 | L II | Negative | <0.2 | B | |
| 73 | PTC | pT2NxMx | 11 | 3.6 | <60 | 1 | R III | ND | 245.7 | M |
| 74 | PTC | pT2NxMx | 29 | 2.2 | <60 | 2 | L III-IV | CTM | 67.4 | IV M, III B |
| 75 | PTC | pT2N1Mx | 14 | 5.7 | <60 | 1 | L II | CTM | 198.7 | M |
| 76 | PTC | pT1N0Mx | 8 | 1.5 | <60 | 1 | R IV | CTM | 26.1 | M |
| 77 | PTC | pT2NxMx | 10 | 2.1 | <60 | 1 | VI | CTM | 59.7 | M |
| 78 | PTC | pT1NxMx | 18 | 0.7 | <60 | 1 | R IV | Negative | <0.2 | B |
| 79 | PTC | pT3N1Mx | 34 | 12.3 | <60 | 1 | R III | ND | 678.4 | M |
| 80 | PTC | pT1N1Mx | 16 | 1.8 | <60 | 1 | L II | Negative | <0.2 | B |
| 81 | PTC | pT2N0Mx | 52 | 0.9 | <60 | 1 | R III | Negative | <0.2 | B |
| 82 | PTC | pT2N1Mx | 25 | 9.4 | <60 | 1 | L III | ND | 563.6 | M |
| 83 | PTC | pT1NxMx | 9 | 4.1 | <60 | 1 | VI | CTM | 64.7 | M |
| 84 | PTC | pT2N1Mx | 18 | 3.1 | <60 | 1 | R IV | CTM | 116.4 | M |
| 85 | PTC-TCV | pT2NxMx | 20 | 15.5 | <60 | 3 | R IV-L III | CTM | 432.9 | M |
| 86 | PTC | pT3N0Mx | 8 | <0.2 | 56 | 1 | VI | ND | <0.2 | B |
| 87 | PTC | pT1N0Mx | 31 | 2.9 | <60 | 1 | R IV | CTM | 39.3 | M |
| 88 | PTC | pT2NxMx | 11 | 1.7 | <60 | 1 | R III | Negative | <0.2 | B |
| 89 | PTC | pT2NxMx | 54 | 6.5 | <60 | 1 | L IV | ND | 467.7 | M |
| 90 | PTC | pT1N1Mx | 28 | 0.3 | 651 | 1 | R II | Negative | <0.2 | B |
| 91 | PTC | pT2NxMx | 12 | 2.1 | <60 | 1 | L III | CTM | 88.6 | M |
| 92 | PTC | pT3N0Mx | 17 | 9.4 | <60 | 2 | R IV, VI | CTM | 156.2 | IV M, VI B |
| 93 | PTC | pT1NxMx | 22 | 1.0 | <60 | 1 | L IV | Negative | <0.2 | B |
| 94 | PTC | pT2N1Mx | 9 | 4.3 | <60 | 1 | VI | Negative | 53.8 | M |
| 95 | PTC | pT2N0Mx | 26 | <0.2 | <60 | 1 | R IV | Negative | <0.2 | B |
| 96 | PTC | pT1N0Mx | 12 | 0.9 | <60 | 1 | R III | ND | 2.7 | M |
| 97 | PTC | pT2NxMx | 17 | 8.1 | <60 | 1 | L II | ND | 356.4 | M |
| 98 | PTC | pT2NxMx | 9 | 0.9 | <60 | 1 | R III | CTM | 19.6 | M |
| 99 | PTC | pT3N1Mx | 12 | 1.1 | <60 | 1 | L III | ND | 0.6 | B |
| 100 | FTC | pT1N1Mx | 45 | 4.9 | <60 | 1 | R III | CTM | 117.5 | M |
| 101 | FTC | pT3N0Mx | 36 | 1.4 | <60 | 1 | R III | Negative | <0.2 | B |
| 102 | FTC | pT2N1Mx | 11 | <0.2 | >1000 | 2 | R III-IV | Negative | <0.2 | B |
| 103 | FTC (HC) | pT1NxMx | 72 | 10.4 | <60 | 1 | R IV | ND | 278.9 | M |
| 104 | FTC | pT2N1Mx | 11 | 0.7 | <60 | 1 | R III | Negative | <0.2 | B |
| 105 | FTC | pT1N0Mx | 18 | 2.1 | <60 | 1 | R IV | CTM | 74.4 | M |
| 106 | FTC (HC) | pT1N0Mx | 6 | 1.9 | <60 | 1 | L III | Negative | 0.8 | B |
| 107 | FTC | pT2N1Mx | 25 | 7.8 | <60 | 1 | R II | ND | 116.4 | M |
| 108 | FTC | pT1NxMx | 19 | 4.6 | <60 | 2 | L II-III | CTM | 89.5 | M |
FNA, fine-needle aspiration; PTC, papillary thyroid carcinoma; FTC, follicular thyroid carcinoma; TCV, tall-cell variant; HC Hürtle cell; R, right, L, left; duration, time from thyroid ablation to FNA; II-III-IV, upper, middle, lower neck lateral compartment, IV, central neck compartment.