Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 1999 May;6(3):317–330.

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 1999, Cold Spring Harbor Laboratory Press

PMC Copyright notice

TGF-β1 induces a long-term increase in sensory neuron excitability. (A) Examples of the spike trains evoked by current injection before, 24- and 48-hr after treatment with TGF-β1 or BSA (control) for 6 hr. Calibration bar, 100 msec, 20 mV. (B) Summary data of excitability changes at the 24- and 48-hr time points. Bars, means ± s.e.m. of the normalized excitability. Two-way ANOVA with repeated measures revealed a significant difference between the treatments of TGF-β1 (solid bars) and the control (open bars) (F_1,8 = 5.47, P < 0.05). (C) Summary data showing that TGF-β1 induces a long-term decrease in sensory neuron firing threshold. Bars, means ± s.e.m. of the normalized current necessary to evoke one action potential (F_1,8 = 8.59, P < 0.05).

TGF-β1 induces a long-term increase in sensory neuron excitability. (A) Examples of the spike trains evoked by current injection before, 24- and 48-hr after treatment with TGF-β1 or BSA (control) for 6 hr. Calibration bar, 100 msec, 20 mV. (B) Summary data of excitability changes at the 24- and 48-hr time points. Bars, means ± s.e.m. of the normalized excitability. Two-way ANOVA with repeated measures revealed a significant difference between the treatments of TGF-β1 (solid bars) and the control (open bars) (F_1,8 = 5.47, P < 0.05). (C) Summary data showing that TGF-β1 induces a long-term decrease in sensory neuron firing threshold. Bars, means ± s.e.m. of the normalized current necessary to evoke one action potential (F_1,8 = 8.59, P < 0.05).