Table 1.
Induction of LTH in the nociceptive neurons
| Spikesa
|
Threshold
|
|||||
|---|---|---|---|---|---|---|
| Day
|
left
|
right
|
left
|
right
|
N
|
SNb
|
| Operated | ||||||
| 0 | 3.7 ± 0.3 | 4.0 ± 0.3 | 1.4 ± 0.1 | 1.4 ± 0.1 | 5 | 34 |
| 1 | 2.7 ± 0.2 | 3.7 ± 0.6 | 1.2 ± 0.1 | 1.4 ± 0.2 | 4 | 15 |
| 4 | 5.6 ± 0.6 | 5.1 ± 0.5 | 1.0 ± 0.1 | 1.2 ± 0.1 | 5 | 30 |
| Gauze | ||||||
| 4 | 8.4 ± 0.6 | 6.1 ± 0.4 | 1.0 ± 0.1 | 1.0 ± 0.6 | 11 | 65 |
| TGFβ1 | ||||||
| 1 | 8.1 ± 0.6 | 4.5 ± 0.4 | 0.9 ± 0.04 | 1.1 ± 0.03 | 4 | 40 |
The number of action potentials elicited by a stimulus normalized to threshold, and the cell threshold (nA) of sensory neurons in the right and left pleural ganglion after an incision (operated), insertion of gauze, or exposure to TGFβ1.
a
The side exposed to TGFβ1. Each value is the mean (±s.e.m.) of the average scores from N animals. Each animal contributed an average score from 5–10 cell pairs—one cell in each pair from the right sensory cluster and the other from the left.
b
(SN) The total number of sensory neuron pairs.