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. 1999 May;6(3):243–256.

Figure 5.

Figure 5

Effects of NT-3 on whole slices from neonatal hippocampus. (A) Effect on the MAPK and PI3K pathways. The whole slices from p12–13 hippocampus were treated with or without NT-3 (4 nm) for 30 min and then harvested for MAPK and Akt assays as described. (B) Effect on synaptic responses to HFS. The p12–13 slices were stimulated with a train of HFS (100 Hz, 1 sec) before and 3 hr after application of NT-3 (4 nm). (Open bars) Control; (hatched bars) NT-3. The synaptic responses to HFS were measured the same way as in Fig. 4.