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Enhancement of glutamateinduced current is prevented by bath application of staurosporine. (A) Superimposed example traces showing the response to glutamate iontophoresis prior to, and 20 min after, application of BDNF in the presence of 1 μm staurosporine. The two traces are essentially indistinguishable. (B) Time course showing that bath application of staurosporine completely prevented the increase in the glutamate-activated current normally seen following exposure to BDNF (n = 4).
