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. 2011 May 17;2:319. doi: 10.1038/ncomms1324

Figure 2. Quantitative comparison of editing for different triplets.

Figure 2

Bottom plots of a–d show the 16 possible triplet contexts on the x axis with edited A in the centre, ordered according to hADAR1 preferences. 406 adenosines were used to determine the average percentage of the population edited in each triplet context, which is plotted on the y axis and normalized as described (see Methods). The 99% confidence interval (CI) for sample averages is indicated by shading. Top plots show differences in average percentage editing between compared proteins, with values for each triplet shown as black ovals and 99% confidence intervals as vertical lines. Panels show comparisons of triplet preferences for (a) hADAR1 compared with hADAR1-D, (b) hADAR2 compared with hADAR2-D, (c) hADAR1 compared with hADAR2 and (d) hADAR1-D compared with hADAR1-D. See Methods for a description of statistical methodology.