Table 1.

Goals of computational model to match with experimental observations.

VEGF Metric	Effect of a decrease in isoform length	Effect of VEGF cleavage
Level of Soluble VEGF	↑ [21]	↑ [7]
Level of Bound VEGF	↓ [24]	↓ [19] *
Level of Total VEGF	= [7] *	= [7,19] *
Magnitude of soluble VEGF gradients	↓ [13]	↓ [17]
Spatial Range of soluble VEGF	↑ [12]	↑ [17]

Note the concordance of the outcomes of decreased isoform length and VEGF cleavage.

* hypothesized, or some supporting evidence, but no definitive experimental confirmation