Figure 1.

Clinical Features of Affected Individuals and Linkage to Chromosome 3 and Identification of Mutations in PLCD1

(A) Complete nail plate leukonychia involving all the finger and toe nails in affected individuals from both recessive families.

(B) Results of autozygosity mapping in family A. The maximum LOD score was obtained for a region on chromosome 3.

(C) Haplotype analysis in families A, B, C, and D. The linked haplotype is indicated in red, and key recombination events are indicated by arrows.