Table 1.
Characteristics of Cases and Controls in the Study
| Dataseta |
GWAS Dataset |
FD1 (WZ) |
FD2 (CD) |
FD3 (GD-HK) |
Combined |
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | Cases | Controls | Cases | Controls | Cases | Controls | Cases | Controls | |
| Number of samples | 419 | 669 | 843 | 2525 | 549 | 1890 | 1411 | 1227 | 3222 | 6311 |
| Female | 183 (43.7%) | 284 (42.5%) | 509 (60.4%) | 1462 (57.9%) | 336 (61.2%) | 1108 (58.6%) | 708 (50.2%) | 641 (52.2%) | 1736 (53.9%) | 3495 (55.4%) |
| Male | 236 (56.3%) | 385 (57.5%) | 334 (39.6%) | 1063 (42.1%) | 213 (38.8%) | 782 (41.4%) | 703 (49.8%) | 586 (47.8%) | 1486 (46.1%) | 2816 (44.6%) |
| Average age (years)b | 34.29 ± 14.12 | 32.68 ± 13.50 | 35.42 ± 15.44 | 44.21 ± 15.37 | 39.65 ± 15.72 | 57.44 ± 13.73 | 38.17 ± 16.43 | 46.55 ± 13.96 | 37.19 ± 15.58 | 47.41 ± 14.02 |
| Refractive errors (Diopters)b | ||||||||||
| ODc | −10.64 ± 4.27 | −13.13 ± 4.59 | −11.34 ± 4.33 | −12.89 ± 3.62 | −12.38 ± 4.12 | |||||
| OSd | −10.32 ± 4.11 | −12.32 ± 4.52 | −10.93 ± 4.07 | −12.57 ± 3.83 | −11.93 ± 4.06 | |||||
| Axial length (mm)b | ||||||||||
| OD c | 27.32 ± 1.71 | 28.74 ± 2.71 | 27.57 ± 1.77 | 28.38 ± 2.12 | 28.17 ± 2.15 | |||||
| OS d | 27.17 ± 1.44 | 28.26 ± 2.63 | 27.43 ± 1.52 | 28.31 ± 2.17 | 28.01 ± 2.08 | |||||
a
GWAS dataset: Shanghai cohort. FD1: follow-up dataset 1, Wenzhou cohort. FD2, follow-up dataset 2, Chengdu cohort. FD3, follow-up dataset 3, Guangdong-Hong Kong cohort.
b
± standard deviation.
c
OD, right eye.
d
OS, left eye.