Table 3. Clustered findings for diagnosis of cervical spine myelopathy.
Clustered results | Sensitivity (95% CI) | Specificity (95% CI) | Positive likelihood ratio (95% CI) | Negative likelihood ratio (95% CI) | Post-test probability of CTS (%) |
1 of 5 positive tests | 0.94 (0.89–0.97) | 0.31 (0.27–0.32) | 1.4 (1.2–1.4) | 0.18 (0.12–0.42) | 43 |
2 of 5 positive tests | 0.39 (0.33–0.46) | 0.88 (0.84–0.92) | 3.3 (2.1–5.5) | 0.63 (0.59–0.79) | 64 |
3 of 5 positive tests | 0.19 (0.15–0.20) | 0.99 (0.97–0.99) | 30.9 (5.5–181.8) | 0.81 (0.79–0.87) | 94 |
4 of 5 positive tests | 0.09 (0.06–0.09) | 1.0 (0.98–1.0) | Inf (3.9–Inf) | 0.91 (0.90–0.95) | 99+ |
Note: Five tests are included in the rule: (1) gait deviation; (2) +Hoffmann’s test; (3) inverted supinator sign; (4) +Babinski test; and (5) age >45 years. The associated post-test probability values are based on a pre-test probability of 35%.