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. 2000 May;7(3):170–179. doi: 10.1101/lm.7.3.170

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Copyright © 2000, Cold Spring Harbor Laboratory Press

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Performance of BL/6, DBA/2, CBA, and 129/SvEms mice in the Barnes circular platform maze. The average distance from the goal tunnel was plotted versus blocks of days. There was no significant difference between BL/6, DBA/2, CBA, and 129/SvEms mice in the first two blocks. However, BL/6 mice performed significantly better than CBA mice in locating the tunnel on the third (F_1,11 = 2.94, P < 0.01) and fourth (F_1,11 = 3.25, P < 0.01) blocks. Similarly, BL/6 mice were significantly better in locating the tunnel than DBA/2 mice on the third (F_1,12 = 3.50, P < 0.01) and fourth (F_1,11 = 2.12, P < 0.05) blocks. BL/6 mice were also significantly better in locating the tunnel than 129/SvEms mice on the third block (F_1,13 = 2.37, P < 0.05). However, there was no significant difference on the fourth block (F_1,13 = 1.85, P > 0.05).