Table 2.
Linear correlations between the IVGTT and the glucose clamp.
| Y | X | Equation | Time period |
r2 | 25th-75th percentiles of prediction error | |
|---|---|---|---|---|---|---|
| Mbw |  |
Y = -172 + 1040 X | 75 min | 0.63 | -10% | +16% |
| Y = -201 + 1179 X | 40 min | 0.63 | -8% | +20% | ||
| Y = -219 + 1256 X | 30 min | 0.62 | -12% | +26% | ||
| Same equation, but using total insulin AUC | Y = -220 + 1310 X | 75 min | 0.68 | -11% | +9% | |
| Y = -218 + 1287 X | 40 min | 0.63 | -8% | +12% | ||
| Y = -248 + 1419 X | 30 min | 0.66 | -8% | +20% | ||
| Mbw |  |
Y = -19 +124 X | Baseline "Quicki" |
0.41 | -14% | +11% |
| Mbw | SI of MINMOD 10-5 | Y = 36 + 0.38 X | 75 min | 0.34 | -16% | +24% |
Equations compare the cellular uptake of glucose obtained by the glucose clamp (Mbw,; μmol min-1 kg-1) and indices of glucose kinetics and plasma insulin obtained during an intravenous glucose tolerance test (IVGTT) in 20 non-obese volunteers.
T1/2 = half-life of exogenous glucose (units: min)
Glucoseo, Inso = plasma concentrations of glucose and insulin at baseline (units: mmol L-1 and pmol L-1)
AUCins = area under the curve for plasma insulin over time (unit: pmol min L-1)
MINMOD = "minimal model analysis" according to Bergman et al. [6]