Influence of 0.2 mm l-fucose and d-fucose on paired-pulse facilitation (PPF) in the hippocampal CA1 region when using a fixed interstimulus interval of 50 msec and increasing stimulus intensity. (Abscissa) Paired-pulse ratio of the fEPSP-slope (sf); (ordinate) stimulus intensity: 1 = threshold intensity; 2, 3, and 4 = threshold intensity times 1.5, 2, and 2.5, respectively. (A) Control records with d-fucose application (N = 6 animals). (B) l-fucose application (N = 8 animals). (*) P < 0.05. (□) Predrug period; (▵) 60 min after beginning of the fucose application; (○) after washout; (vertical bars) s.e.m. Inserts in (A) and (B) show analogous examples of the fEPSP evoked by near-threshold intensity (I = before, II = during substance application, III = after washout).