FIG. 7.

Scatterplots show the relationship between weight-bearing stepping recovery and synaptophysin labeling around motor neurons (A), BDNF labeling in the ventral horn (C), and TrkB labeling in the ventral horn (E). The square, triangle, and diamond symbols represent data from individual rats in the 0, 100, and 1000 groups respectively. The dashed lines are for the data points for the 0, 100, and 1000 groups. The solid black line is for the combined data points from all groups. Stepping recovery was measured as the percentage of steps that were weight bearing during 30 sec of testing. The Pearson correlation coefficients are shown for the relationships between stepping and synaptophysin label (B), BDNF label (D), and TrkB label (F). In these plots, the bar on the left is the correlation between synaptophysin, BDNF, or TrkB label and weight-bearing steps performed during testing. The bar on the right is the correlation between label and total number of steps imposed during 4 weeks of training. Combined data fromall on the right groups were used in these plots. * and ** indicate significant relationships at the p<0.05 and p<0.01 levels.