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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Nat Med. 2011 May 22;17(6):684–691. doi: 10.1038/nm.2388

Figure 5.

Figure 5

Bone mass in WT and Tph1−/− mice. (a) Graphs depicting femoral trabecular BV/TV in WT and Tph1−/− mice on either FVB/N or C57BL/6 backgrounds (left) or on a mixed 129SvEvBrd/C57BL/6J-Tyrc-Brd background (right). (b) Graphs depicting the vertebral trabecular BV/TV of the 5th lumbar vertebra in the same mice described in panel a. (c) Graphs depicting lumbar spine aBMD, as measured by DEXA, in the same mice described in panel a. The numbers of mice studied (n =) are indicated, as are 1 s.d. error bars. Asterisks (*) indicate a significant difference (p < 0.05) compared to WT mice using an unpaired t-test; none of these differences remain significant after correcting for multiple testing.