| Adequate |
| Conceptualization of QoL |
| Comprehensive strategy for recruiting participants |
| Use of validated, multidimensional QoL instrument |
| Analytically rigorous, including attainment of sufficient sample size and use of appropriate control/comparison group |
| Reported |
| Specific objectives and hypotheses |
| Clear description of study design, recruitment source, inclusion and exclusion criteria |
| Sample characteristics and demographics |
| Clearly defined key variables and measures |
| Comprehensive presentation of QoL data on all domains of instrument |
| Detailed description of analyses performed and statistical significance of results |
