Table 1.
Cause for mortality in mice transplanted with Lsh−/− and Lsh−/−p53−/− donor cells
| Lsh+/+ (n = 10) | Lsh−/− (n = 15) | Lsh−/−p53−/− (n = 22) | Lsh+/+p53−/− (n = 12) | |
|---|---|---|---|---|
| Anemia | 0% | 27% (n = 4) | 5% (n = 1) | 0% |
| Infection/Inflammation | 10% (n = 1) | 60% (n = 9) | 36% (n = 8) | 0% |
| Pneumonia | 5% (n = 1) | |||
| Typhocolitis | 13% (n = 5) | 14% (n = 3) | ||
| Dermatitis | 20% (n = 3) | 14% (n = 3) | ||
| Myositis | 7% (n = 1) | 5% (n = 1) | ||
| Otitis media | 10% (n = 1) | |||
| Other* | 90% (n = 9) | 13% (n = 2) | 59% (n = 13) | 100% (n = 12) |
Other reasons include tumors and undetermined causes of death.