Table 4. Cox Proportional Hazards Models: Predictors of Incident Heart Failure by Sex.

	Model 1*		Model 2*		Model 3*
	Hazard Ratio	95% CI	Hazard Ratio	95% CI	Hazard Ratio	95% CI
Women
Age per 10-year increase	2.31	2.25–2.37	…	…	1.86	1.80–1.92
Hypertension	11.46	10.26–12.80	4.07	3.62–4.59	3.18	2.80–3.60
Diabetes	6.02	5.48–6.62	2.93	2.67–3.23	2.03	1.84–2.37
Coronary heart disease	12.11	10.80–13.57	3.17	2.81–3.57	2.09	1.85–2.37
Atrial fibrillation	16.35	13.93–19.20	2.90	2.46–3.42	2.05	1.73–2.44
Valvular heart disease	4.79	4.12–5.58	1.78	1.53–2.08	1.07	0.91–1.26
Men
Age per 10-year increase	2.32	2.25–2.39	…	…	1.80	1.74–1.87
Hypertension	10.05	9.06–11.16	3.97	3.56–4.45	3.00	2.66–3.39
Diabetes	5.40	4.91–5.94	2.43	2.20–2.67	1.71	1.55–1.89
Coronary heart disease	9.15	8.29–10.11	2.87	2.58–3.19	1.79	1.60–1.99
Atrial fibrillation	11.33	9.76–13.16	2.86	2.45–3.34	2.03	1.73–2.38
Valvular heart disease	6.97	5.95–8.16	2.21	1.88–2.59	1.39	1.18–1.64

CI indicates confidence interval.

^*Model 1 is unadjusted for any other risk factors. Model 2 is adjusted for age only. Model 3 is fully adjusted for age plus all other risk factors.