Table 6. Cox Proportional Hazards Models: Predictors of Incident Heart Failure Diagnosed on an Inpatient or an Outpatient Basis.
| Model 1* | Model 2* | Model 3* | ||||
|---|---|---|---|---|---|---|
| Hazard Ratio | 95% CI | Hazard Ratio | 95% CI | Hazard Ratio | 95% CI | |
| Inpatients | ||||||
| Age, per 10-year increase | 2.45 | 2.37–2.54 | … | … | 1.76 | 1.69–1.84 |
| Female sex | 0.92 | 0.83–1.02 | … | … | 0.96 | 0.86–1.07 |
| Hypertension | 18.82 | 16.10–22.01 | 7.04 | 5.97–8.30 | 4.64 | 3.90–5.52 |
| Diabetes | 8.18 | 7.34–9.13 | 3.77 | 3.37–4.21 | 2.41 | 2.16–2.70 |
| Coronary heart disease | 15.55 | 13.84–17.47 | 4.52 | 3.98–5.12 | 2.32 | 2.04–2.64 |
| Atrial fibrillation | 25.50 | 21.99–29.58 | 5.38 | 4.60–6.30 | 3.22 | 2.74–3.78 |
| Valvular heart disease | 9.88 | 8.50–11.48 | 3.42 | 2.93–4.00 | 1.74 | 1.48–2.04 |
| Outpatients | ||||||
| Age, per 10–year increase | 2.26 | 2.21–2.32 | … | … | 1.90 | 1.85–1.96 |
| Female sex | 0.84 | 0.78–0.90 | … | … | 0.82 | 0.76–0.89 |
| Hypertension | 8.61 | 7.89–9.40 | 3.25 | 2.95–3.57 | 2.68 | 2.42–2.96 |
| Diabetes | 4.80 | 4.41–5.24 | 2.24 | 2.06–2.45 | 1.63 | 1.49–1.78 |
| Coronary heart disease | 8.50 | 7.70–9.38 | 2.47 | 2.23–2.74 | 1.75 | 1.58–1.95 |
| Atrial fibrillation | 9.01 | 7.63–10.63 | 1.96 | 1.66–2.33 | 1.53 | 1.29–1.82 |
| Valvular heart disease | 3.64 | 3.09–4.29 | 1.34 | 1.13–1.58 | 0.92 | 0.78–1.09 |
CI indicates confidence interval.
Predictors of incident HF are shown separately for inpatients and outpatients.
Model 1 is unadjusted for any other risk factors. Model 2 is adjusted for age and sex. Model 3 is adjusted for age, sex, and all other risk factors.