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. Author manuscript; available in PMC: 2012 Jun 1.

Published in final edited form as: Neurourol Urodyn. 2011 Jun;30(5):673–682. doi: 10.1002/nau.21078

Four (A) and 24 hours (B) after instillation of acrolein (6, 10, or 100 μg; 15 μl total volume) or 15 μl phosphate buffered saline (PBS; control) into the bladders of female C57BL6N mice, it was observed that the severity of inflammation as indicated by intramural edema and hemorrhage correlated with increasing concentrations of acrolein. (L, lumen; D, detrusor); 40x original; scale bar = 200 μm. (With permission from: Bjorling DE, Elkahwaji JE, Bushman W, Janda LM, Boldon K, Hopkins WJ, Wang ZY. Acute acrolein-induced cystitis in mice. BJU Int 2007;99:1523-1529.)

Four (A) and 24 hours (B) after instillation of acrolein (6, 10, or 100 μg; 15 μl total volume) or 15 μl phosphate buffered saline (PBS; control) into the bladders of female C57BL6N mice, it was observed that the severity of inflammation as indicated by intramural edema and hemorrhage correlated with increasing concentrations of acrolein. (L, lumen; D, detrusor); 40x original; scale bar = 200 μm. (With permission from: Bjorling DE, Elkahwaji JE, Bushman W, Janda LM, Boldon K, Hopkins WJ, Wang ZY. Acute acrolein-induced cystitis in mice. BJU Int 2007;99:1523-1529.)