Table 2.

ECM proteins and adhesion molecules down-regulated by rapamycin in fibroblasts at the transcriptional level

Gene Bank	Gene Name	Description	X fold (decrease)
NM_175643	4732482M10, A430089F14, ADAM-TS2, ADAMTS-3, KIAA4060, PCINP, hPCPNI, mKIAA4060	A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2	3.9 ↓
NM_011782	9530092O11Rik, ADAM-TS5, ADAMTS1, ADAMTS11, AI481094, ASMP-2	A disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)	1.5 ↓
NM_007727	AW495098, CNTN, F3cam	Contactin 1	2.2 ↓
NM_007734	[a]3(IV), alpha3(IV), tumstatin	Collagen, type IV, alpha 3	2.1 ↓
NM_133918	5830419M17Rik, AW229038, BB105748, EMILIN-1, gp115	Elastin microfibril interfacer 1	2.0 ↓
NM_010180	-	Fibulin 1	2.1 ↓
NM_010406	C5, C5a, He	Hemolytic complement	1.6 ↓
NM_008404	2E6, AI528527, Cd18, LAD, LCAMB, Lfa1, MF17	Integrin beta 2	1.5 ↓
NM_008481	5830440B04, KIAA4087, dy, mKIAA4087, mer, merosin	Laminin, alpha 2	1.9 ↓
NM_010683	Lamb2	Laminin, gamma 1	1.9 ↓
NM_010809	SLN-1, SLN1, STR-1, Stmy1, Str1	Matrix metallopeptidase 3	1.5 ↓
NM_010810	MAT	Matrix metallopeptidase 7	1.5 ↓
NM_011580	TSP-1, TSP1, Thbs-1, tbsp1	Thrombospondin 1	2.7 ↓
NM_011581	TSP2, Thbs-2	Thrombospondin 2	1.5 ↓
NM_013691	TSP3, Thbs-3	Thrombospondin 3	2.4 ↓
NM_011594	D11Bwg1104e, Timp-2	Tissue inhibitor of metalloproteinase 2	4.3 ↓