Table 2.

Non-compartmental pharmacokinetic analysis of S-PAC-1 (25 mg/kg) in four healthy research dogs.

Parameters	Hound A	Hound B	Hound C	Hound D
Body weight (kg)	33.2	34.1	34.2	32.5
Lambda_z half-life (h)	1.05	1.11	1.11	1.09
Tmax (h)	0.17	0.17	0.17	0.17
Cmax (ug/ml)	69.86	63.71	80.07	69.83
AUC0-inf h*ug/ml	73.56	74.60	82.19	78.81
AUMC0-inf h*h*ug/ml	93.63	104.77	90.48	101.78
Cls (ml/h/kg)	340	335	304	317
Vss (ml/kg)	432.5	470.8	334.8	410
MRT (h)	1.27	1.40	1.10	1.29