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. Author manuscript; available in PMC: 2011 Jun 13.
Published in final edited form as: Bioorg Med Chem Lett. 2010 Mar 7;20(8):2448–2451. doi: 10.1016/j.bmcl.2010.03.020

Figure 2.

Figure 2

Simplified scheme for the reaction of oxaliplatin with DNA (the location of the 14C atom is asterisked). Because radiocarbon is located in the DACH carrier group, radiocarbon in oxaliplatin–DNA monoadducts and diadducts can be detected by AMS.