Figure 1.

In vivo depolarization signals for spike initiation and subthreshold are long-time in nature. A) The integrated synaptic signals induce spikes. B) shows the integrated synaptic signals at subthreshold level (top panel) and the expanded waveforms (bottoms), which appear steady-state pattern (square pulse) and fluctuation one (cosine). C) shows number of EPSPs in vivo vs. signal durations, which fall into a range of 50~1600 ms. D) illustrates the percentages for steady-state pattern and fluctuation one analyzed from total in vivo signals (n = 11 neurons).