Table 2.
Gene ontologies with differentially expressed genes in bone marrow adipocytes
| Functional Group | Enrichment Score* | P value** | % genes in group present |
|---|---|---|---|
| Biological process | 4.39 | 0.01 | 18.10 |
| Cellular | 40.9 | <0.001 | 21.9 |
| Immune system | 18.36 | <0.001 | 31.7 |
| Metabolic | 16.67 | <0.001 | 20.7 |
| Oxidation reduction | 37.36 | <0.001 | 30.52 |
| Lipid | 23.63 | <0.001 | 34.7 |
| Carbohydrate | 7.41 | <0.001 | 28.05 |
| Developmental | 4.3 | 0.01 | 19.71 |
| Adipocyte differentiation | 18.3 | <0.001 | 47.27 |
| Brown | 31.44 | <0.001 | 74.07 |
| White | 8.46 | <0.001 | 71.43 |
| Cellular component | 3.55 | 0.03 | 17.97 |
| Molecular component | 1.80 | 0.17 | 17.91 |
A selection of genes generated from ANOVA analysis was assigned to biologically meaningful gene ontology (GO) categories using GO enrichment analysis (Partek® Genome Suite software, version 6.3). Listed are groups of gene-associated biological processes in bone marrow adipocytes compared with epididymal adipocytes (fold change cut off is 2.0). *A high value of enrichment score indicates that the functional group is over-represented in the gene list. **P value is the -log p-value of a Chi-square test.