Figure 4.

ZFN-Site returns sites found in previous CCR5 ZFN off-target analysis. The sequences returned by ZFN-Site were matched to the sequences found by Perez et al. For clarity of presentation, the ZFN-Site output was arranged to match the order of Perez et al. ZFN-Site found all the sites found by the unpublished algorithm of Perez et al., thus validating ZFN-Site. We replaced the column containing the genome browser links with a column referencing the order listed in the first column of Perez, et al. Columns detail the human sequences matching the query, the chromosomal coordinates and the strand. The first row consists of the exact match to the CCR5 genomic sequence.