Table 1.
Classification of MT-Isomers
| S.No | Based on | Classification | |
|---|---|---|---|
| 1. | Metals Present | Major -MT-1 &MT-2 | |
| Minor - MT-3 &MT-4 | |||
| 2. | Proteins are encoded by a family of genes which are located on chromosome 16q13 | MT I a, MT I b, MT I c etc | |
| 3. | Biological system | Central nervous system | MT-I, MT-II and MT-III |
| Neurons | MT-III | ||
| 4. | Family of eukaryote and some are in prokaryote | Proteins with sequences related to mammalian MT | MT- i |
| Proteins with sequences not related to mammalian MT | MT- ii | ||
| Peptides that are not genetically encoded | MT- iii | ||
| 5. | Expressed in tissues | Liver and kidney | MT-I and MT-II |
| Brain and to male reproductive organs | MT-III | ||
| Specific to stratified squamous epithelia | MT-IV | ||