TABLE 1.
SUBJECT CHARACTERISTICS AND BASELINE LUNG FUNCTION MEASURES
| All Subjects | Males | Females | GSTM1-p | GSTM1-n | |
|---|---|---|---|---|---|
| No. | 59 | 27 | 32 | 30 | 29 |
| Age, yr | 25.0 (0.5) | 26.1 (0.9) | 24.0 (0.5) | 24.9 (0.8) | 25.1 (0.7) |
| Height, cm | 171.2 (1.2) | 178.9 (1.2) | 164.7 (1.0) | 172.2 (1.5) | 170.2 (1.9) |
| Weight, kg | 70.5 (1.8) | 78.8 (2.3) | 63.4 (2.1) | 71.5 (2.5) | 69.4 (2.6) |
| BSA, m2 | 1.8 (0.03) | 2.0 (0.03) | 1.7 (0.03) | 1.8 (0.04) | 1.8 (0.04) |
| BMI, kg/m2 | 23.8 (0.48) | 24.5 (0.72) | 23.3 (0.64) | 23.9 (0.68) | 23.8 (0.69) |
| FEV1, L | 4.02 (0.10) | 4.64 (0.12) | 3.49 (0.07) | 4.14 (0.12) | 3.89 (0.16) |
| FVC, L | 4.83 (0.13) | 5.69 (0.14) | 4.10 (0.11) | 4.94 (0.17) | 4.72 (0.21) |
| FEV1/FVC, % | 84.1 (0.8) | 82.0 (1.1) | 85.8 (1.2) | 84.6 (1.2) | 83.5 (1.2) |
| FEF25-75%, L/s | 4.22 (0.14) | 4.64 (0.23) | 3.87 (0.14 | 4.39 (0.21) | 4.05 (0.18) |
| FEFmax, L/s | 9.03 (0.25) | 10.61 (0.28) | 7.69 (0.17) | 9.49 (0.35) | 8.54 (0.34) |
Definition of abbreviations: BMI = body mass index; BSA = body surface area; FEF25-75% = forced expiratory flow between 25 and 75% of FVC; FEFmax = maximum forced expiratory flow; GSTM1-n = glutathione S-transferase mu 1 null; GSTM1-p = glutathione S-transferase mu 1 positive.
Values are mean (± SEM)