FIG. 1.

Effect of PDBu on phenylephrine-induced contractions of uterine arteries in long-term, high-altitude hypoxic sheep. Phenylephrine-induced contractions were determined in the uterine arteries obtained from nonpregnant and pregnant ewes acclimatized to high altitude hypoxia in the absence or presence of PDBu (100 nmol/L, pretreatment for 10 min). GF109203X (1 μmol/L, pretreatment for 20 min) was added before PDBu in uterine arteries of pregnant animals. Data are means ± SEM of the tissues from 5 to 12 animals.