Table 1.
MMP-2 | MMP-3 | MMP-8 | MMP-9 | MMP-10 | MMP-12* | MMP-13* | MMP-14 | TIMP-1 | TIMP-2 | TIMP-3 | |
---|---|---|---|---|---|---|---|---|---|---|---|
nude | 5.69±1.8 | 1.79±0.3 | 0.11±0.1 | 2.95±0.7 | 0.58±0.2 | 9.73±3.6 | 2.77±0.8 | 10.7±4.7 | 0.78±0.2 | 7.55±2.4 | 18.77±5.7 |
wild type | 6.15±0.9 | 1.65±0.3 | 0.02±0.01 | 1.88±0.4 | 0.15±0.07 | 1.63±1.05 | 0.60±0.39 | 8.5±1.24 | 0.35±0.07 | 10.88±2.08 | 38.92±9.9 |
Expression of Mmps and Timps mRNA analysed in single skin samples (n=7–9) was normalized by level of cyclophilin B mRNA in the reaction using standard curve method. There were no statistically significant differences in the cyclophilin B mRNA copy numbers between nude and wild type mice. Values are the mean ± SEM (n=7–9);
p<0.05.