Table 2. Laboratory and physiological measurements before and after transfusion.
High Hematocrit Group | Low Hematocrit Group | |||||
---|---|---|---|---|---|---|
Pre-Transfusion | Post-Transfusion | P* | Pre-Transfusion | Post-Transfusion | P* | |
Hemoglobin, g/dl | 13.6 (1.0) | 16.3 (1.6) | <0.0001 | 9.1 (1.4) a | 13.1 (1.4) b | <0.0001 |
Hematocrit, % | 39 (7) | 48 (5) | <0.0001 | 27 (4) a | 38 (4) b | <0.0001 |
RBC count, × 106/μl | 4.1 (0.7) | 5.4 (0.6) | <0.0001 | 2.9 (0.5) a | 4.2 (0.6) b | <0.0001 |
Reticulocyte count, × 103/μl | 53 (20) | 62 (19) | 0.412 | 53 (16) | 61 (21) | 0.586 |
Blood lactic acid, mmol/l | 1.1 (0.2) | 0.7 (0.1) | <0.0001 | 1.1 (0.2) | 0.9 (0.2) | 0.032 |
Plasma erythropoietin, mU/ml | 16 (6) | 14 (6) | 0.596 | 16 (7) | 14 (5) | 0.609 |
Cardiac output, ml/min per kg | 291 (98) | 277 (91) | 0.402 | 301 (101) | 253 (66) | 0.048 |
Arterial oxygen content, ml/dl | 16 (2) | 20 (3) | <0.0001 | 12 (2) a | 17 (2) b | <0.0001 |
Oxygen consumption, ml/min per kg | 8.1 (1.5) | 8.1 (1.1) | >0.99 | 10.0 (1.7) | 9.0 (1.1) | 0.279 |
Systemic oxygen transport, ml/min per kg | 44 (7) | 57 (12) | 0.004 | 33 (4) a | 41 (5) b | 0.001 |
Fractional oxygen extraction | 0.20 (0.08) | 0.17 (0.08) | 0.250 | 0.31 (0.11) a | 0.24 (0.12) b | 0.003 |
Mean FiO2 | 0.31 (0.09) | 0.32 (0.10) | 0.561 | 0.32 (0.11) | 0.31 (0.12) | 0.055 |
Mean oxygen saturation, % | 96 (3) | 96 (3) | 0.563 | 96 (3) | 95 (2) | 0.333 |
Mixed venous O2 content, ml/dl | 13 (2) | 17 (2) | <0.0001 | 8 (2) a | 13 (3) b | <0.0001 |
Values are mean (SD)
Pre-Transfusion vs Post-Transfusion
P<0.05, Pre-Transfusion Low vs Pre-Transfusion High
P<0.05, Post-Transfusion Low vs Post-Transfusion High