Figure 2.

Growth retardation in FgfR2-IIIc^+/Δ mice. (A) Hemizygotes were identifiable at birth by their smaller sizes, characteristic dome-shaped heads, and truncated faces; the genotype was confirmed by PCR using tail genomic DNA (Fig. 1G). (B) All hemizygotes showed growth retardation after birth as reflected in a comparison of their body weights with those of wild-type littermates. Brackets show the number of hemizygotes and wild types analyzed. (C) Table summarizing the major abnormalities and their penetrance (number showing specified defects/total number of hemizygotes analyzed) at E18 and postnatally.