Fig. 9.

Mismatch between the pilot and the actual position of the epithelium layer boundary (manually segmented by a cornea specialist) in the original and dark-to-light gradient image (Fig. 1.c). (a) Pilot epithelium boundary (yellow) and the actual location of the epithelium boundary (blue) delineated over the original image. Note that the actual epithelium goes through the center of the brightest region of the original image. (b) Pilot and the actual epithelium boundary from (a) delineated on the gradient image. Note that the brightest region in the gradient image (b) is not the same as in (a), which results in mismatch between the two lines.