Table 3.

Multivariable adjusted hazards ratios for the association between smoking and early respiratory failure, relapse, or non-relapse mortality, stratified by donor HLA type

Outcome	N (%)	HR	95% CI	p-value
Related matched donor	307 (36%)
Early respiratory failure*		1.83	1.18 to 2.84	0.007
Relapse**		1.21	0.92 to 1.60	0.17
Non-relapse mortality‡		0.99	0.77 to 1.29	0.97
Unrelated matched donor	311 (37%)
Early respiratory failure*		1.46	1.02 to 2.09	0.04
Relapse**		1.44	1.04 to 2.01	0.03
Non-relapse mortality‡		0.91	0.74 to 1.12	0.38

^*Adjusted for age, gender, smoking status, conditioning regimen, acute GVHD

^**Adjusted for age, gender, smoking status, conditioning regimen, disease risk, acute and chronic GVHD

^‡Adjusted for age, gender, smoking status, conditioning regimen, stem cell source, PAM score, acute and chronic GVHD